The Drew Barrymore Show — Season 2

E01 Jennifer Aniston, Wayne Brady, Dr. Phil 13 Sep 2021 E02 Molly Shannon, David Arquette, Michael Vartan 14 Sep 2021 E03 Cameron Diaz 15 Sep 2021 E04 Billie Eilish 16 Sep 2021 E05 Cedric the Entertainer, Kevin Frazier, Nischelle Turner 17 Sep 2021 E06 Awkwafina, Fat Joe, Fran Drescher, Benito Skinner 20 Sep 2021 E07 Carmelo Anthony, Antoni Porowski, Ziwe Fumudoh 21 Sep 2021 E08 John Stamos 22 Sep 2021 E09 Martha Stewart 23 Sep 2021 E10 Ben Platt 24 Sep 2021 E11 Zanna Roberts Rassi, Chris Appleton, Brandice Daniel, Young Emperors, Max Greenfield 27 Sep 2021 E12 Vanessa Hudgens, Zachariah Porter, Mikel Welch 28 Sep 2021 E13 Padma Lakshmi, Damona Hoffman, Leo Kelly 29 Sep 2021 E14 Elmo/Emmy Eaton/Pilar Valdes 30 Sep 2021 E15 Phoebe Robinson #2 01 Oct 2021 E16 Bobby Flay, The Old Gays, Aliza Kelly 04 Oct 2021 E17 50 Cent, Elizabeth and Ethan Finkelstein 05 Oct 2021 E18 Jason Biggs, Ego Nwodin, Mikel Welch, Isaiah Garza 06 Oct 2021 E19 Dakota Johnson, Danny Seo, The Good in Five 07 Oct 2021 E20 The Estefans, Lisa Ling 08 Oct 2021 E21 Adam Lambert, Tracey Cunningham, Ruby Ortiz 11 Oct 2021 E22 Ike Barinholtz, Jonathan Toews, Seth Jones, Larray, Gillian Laub 12 Oct 2021 E23 Chelsea Handler, Gillian Laub, Eitan Bernath 13 Oct 2021 E24 October 14, 2021 - Meridith Hagner 14 Oct 2021 E54 Kathryn Hahn, Jane Levy, Lynn "Lynja" Davis 29 Nov 2021 E55 Brooke Shields, Erin French, Chiké Okonkwo 30 Nov 2021 E56 Sutton Foster, Dionne Warwick, Vanessa Lachey 01 Dec 2021 E57 Michelle Visage, Vanessa Williams, Mary McCartney, Trixie Mattel 02 Dec 2021 E58 Kal Penn, Michael Urie, Eitan Bernath 03 Dec 2021 E59 Ansel Elgort, Haylie Duff, Leo Kelly 06 Dec 2021 E60 Whoopi Goldberg, Rachel Zegler 07 Dec 2021 E61 Kristin Chenoweth, Ben and Erin Napier, Eric André 08 Dec 2021 E62 Ariana DeBose, Jamie Oliver, Mikel Welch 09 Dec 2021 E63 David Alvarez, Mike Faist, Josh Andres Rivera, Machine Gun Kelly, Chef Pilar Valdes 10 Dec 2021 E64 Maya Erskine & Anna Konkle, Chef Pilar Valdes, Danny Pellegrino 13 Dec 2021 E65 Kristin Davis, Gayle King 14 Dec 2021 E66 Jonathan Groff, Amanda Gorman, Lindsey Peers 15 Dec 2021 E67 Aubrey Plaza, Adam Rodriguez, Dan Churchill, Crafty Lumberjacks 16 Dec 2021 E68 Kendrick Sampson, Chef Pilar Valdes 20 Dec 2021 E69 Keanu Reeves 21 Dec 2021 E70 Reese Witherspoon 22 Dec 2021 E71 Victoria Shaffer/Luis Perez and Nyomie Nieves 05 Jan 2022 E73 Courteney Cox 07 Jan 2022 E74 Courteney Cox, David Arquette, Neve Campbell, Chef Pilar Valdes 10 Jan 2022 E75 Fred Savage/EJ Williams/Jenna Ortega 11 Jan 2022 E76 Jonathan Van Ness 12 Jan 2022 E77 Jonathan Van Ness/Antoni Porowski/Bobby Berk/Tan France/Melissa Barrera 13 Jan 2022 E78 John Cena 14 Jan 2022 E80 Mariska Hargitay, Ali Wentworth, Tiki Barber, Jenny Mollen, Jason Biggs 18 Jan 2022 E103 Kat Dennings 18 Feb 2022 E108 Sophia Bush, Nicole Lapin 25 Feb 2022 E113 Sabrina Carpenter, Carla Lalli Music 04 Mar 2022 E114 Greg Kinnear/George Oliphant 07 Mar 2022 E115 Taylor Schilling/Maryline Damour/Donna Pratt 08 Mar 2022 E116 Sam Heughan/Asad Syrkett 09 Mar 2022 E117 Topher Grace/Danny Pellegrino/Mike Jackson and Egypt Sherrod 10 Mar 2022 E118 Michelle Buteau/Cori Bosco/Mikel Welch 11 Mar 2022 E119 Adam Scott/Mama LaVerne & Donna Richardson 14 Mar 2022 E120 Eric Stonestreet/Corinna Cafarelli/Kamryn Reynolds/Drew's News 15 Mar 2022 E121 Scarlett Johansson 16 Mar 2022 E127 Olivia Rodrigo, Amy Schumer, Violet Young 24 Mar 2022 E128 John Cho, Iris Apatow, John Eringman, Kevin Frazier, Nischelle Turner 25 Mar 2022 E129 Ellie Kemper, Chef Jet Tila, Suzanne Somers 28 Mar 2022 E130 Episode 130 29 Mar 2022 E134 Episode 134 04 Apr 2022 E148 Episode 148 22 Apr 2022 E149 Episode 149 25 Apr 2022 E150 Episode 150 26 Apr 2022 E151 Natasha Lyonne, Antoni Porowski, Drew's News 27 Apr 2022 E152 Episode 152 28 Apr 2022 E153 Episode 153 29 Apr 2022 E154 Episode 154 02 May 2022 E181 Episode 181 23 May 2022 E182 Episode 182 24 May 2022 E183 Episode 183 25 May 2022 E184 Episode 184 26 May 2022 E185 Episode 185 27 May 2022 E186 Episode 186 30 May 2022 E187 Episode 187 31 May 2022 E188 Episode 188 01 Jun 2022 E189 Episode 189 02 Jun 2022 E190 Episode 190 03 Jun 2022 E191 Episode 191 06 Sep 2022 E192 Episode 192 07 Sep 2022 E193 Episode 193 08 Sep 2022 E194 Episode 194 09 Sep 2022 E195 Episode 195 12 Sep 2022