Synopsis
Episodes feature heavier fourth-wall breaking, alternative openings (such as Stan's modified morning routine near Groff Community College), and playful call-backs to running gags like "Ricky Spanish". Stan takes the family to a buffet that turns out to be a trap set by CIA scientist Dr. Weitzman, while Roger copes with stress by turning into a flower (which gets bought by a woman cheating on her husband).
Season 18 aired between 19 Apr 2021 and 25 Oct 2021, 22 episodes.
Episodes
E01
Who Smarted?
19 Apr 2021
E02
Russian Doll
26 Apr 2021
E03
Stan Moves to Chicago
03 May 2021
E04
Shakedown Steve
10 May 2021
E05
Klaus and Rogu in "Thank God for Loose Rocks": An American Dad! Adventure
17 May 2021
E06
The Wondercabinet
24 May 2021
E07
Little Bonnie Ramirez
31 May 2021
E08
Dancin' A-With My Cells
07 Jun 2021
E09
Mused and Abused
14 Jun 2021
E10
Henderson
21 Jun 2021
E11
Hot Scoomp
28 Jun 2021
E12
Lumberjerk
05 Jul 2021
E13
Stan & Francine & Stan & Francine & Radika
12 Jul 2021
E14
Flush After Reading
19 Jul 2021
E15
Comb Over: A Hair Piece
26 Jul 2021
E16
Plot Heavy
02 Aug 2021
E17
The Sinister Fate!!
09 Aug 2021
E18
Dr. Sunderson's SunSuckers
16 Aug 2021
E19
Family Time
23 Aug 2021
E20
Cry Baby
30 Aug 2021
E21
Crystal Clear
06 Sep 2021
E22
Steve's Franken Out
25 Oct 2021